Many people with Parkinson's on a levodopa regimen face "off" periods, when the effects of the medication wear off before they are ready to take their next dose. For this reason, The Michael J. Fox Foundation (MJFF) continues to focus much of its resources on finding improved mechanisms of delivering the drug into the body (breath activated inhaler for levodopa).
Enter Civitas Therapeutics, who is working to develop an inhaled formulation of levodopa. Called CVT-301, the therapy is designed to function as a sort of "rescue drug" to be taken in conjunction with the traditional pill form of levodopa/carbidopa (sinemet). The idea is that patients taking CVT-301 could self-medicate by taking a puff from an inhaler should they feel an "off" period coming on.
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